Compare and book 5 Star hotels in Clayton, St. Louis

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Top Clayton 5 Star Hotels

Four Seasons Hotel St Louis
Rooftop bar
Four Seasons Hotel St Louis
5.0 star property
9.4 out of 10, Exceptional, (958)
"The hotel was beautiful. Great restaurant and bar.!! "
The price is 10.393.500 ₫
12.153.044 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis
Meeting facility
The Ritz-Carlton, St. Louis
5.0 star property
9.2 out of 10, Wonderful, (519)
"Staff was not as willing to help as I would’ve expected based on my past experiences at other Ritz Carlton’s."
The price is 13.914.954 ₫
16.209.781 ₫ total
includes taxes & fees
30 Nov - 1 Dec
The Ritz-Carlton, St. Louis
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Clayton.
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St, St. Louis, MO
The price is 2.230.800 ₫ per night from 26 Nov to 27 Nov
2.230.800 ₫
2.630.760 ₫ total
includes taxes & fees
26 Nov - 27 Nov
8.4/10 Very Good! (3,469 reviews)
Still don't see what you're looking for?
See all properties in Clayton.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the best 5-star hotels in Clayton?
Step into a world of luxury at The Ritz-Carlton, St. Louis. This is one of the top 5-star hotels in Clayton according to Expedia guest reviews. From its prime location to its amenities and guest services, you can count on an exceptional guest experience.
How much does it cost to stay in a 5-star hotel in Clayton?
You’ll find various pricing options for a 5-star hotel in Clayton on Expedia. How much you’ll pay will depend on when you plan to travel, length of your trip and other factors. Compare all of the available accommodation for your desired dates and use our pricing and other filters to discover the perfect high-end stay.

  • Search for the lowest price per night from 2.230.800 ₫

What makes a hotel 5 stars in Clayton?
In Clayton, a hotel needs to provide a certain amount of upscale conveniences to be designated 5 stars. These can include on-site gyms, spas and saunas, gourmet restaurants, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their outstanding standard of service. You’ll enjoy things like nightly turn-down services, in-room massages and concierge services. Some may also offer extra touches such as a welcome gift.
Are there any 5-star all-inclusive resorts in Clayton?
Expedia’s filters are the best way to find exactly what you want. Select “All inclusive” and “5-star” to show the most luxurious hotels in Clayton where your meals, accommodation, activities and entertainment are included in the price. At these escapes, your trip is pure relaxation and indulgence from the moment you pull up to the entrance.
What are the top 5-star spa hotels in Clayton?
Book a massage treatment and feel all your stresses instantly melt away at The Ritz-Carlton, St. Louis. This 5-star spa retreat in Clayton provides a selection of rejuvenating treatments and amenities that soothe your body, mind and soul.
Are there any 5-star holiday rentals in Clayton?
Although there aren’t any 5-star holiday rentals in Clayton on our site, we have a range of stays that promise an unforgettable getaway. Discover one that matches your style by searching our holiday rentals in Clayton.
Are there any 5-star hotels in downtown Clayton?
Take a look at The Ritz-Carlton, St. Louis. This 5-star hotel is ideal if you want to immerse yourself in Clayton’s downtown scene.