Photo by Hazem Abdul

Search Hotels in South Main, Houston

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Filter by

Popular filters
Popular filters
Price per night
Guest rating
Guest rating
Property class
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top Trending Hotels Near South Main, Houston

Club Quarters Hotel Downtown, Houston
Lobby sitting area
Club Quarters Hotel Downtown, Houston
4.0 star property
8.2 out of 10, Very good, (4021)
"I love it, just parking is not good to me"
The price is 2.321.770 ₫
per night
28 Jul - 29 Jul
Club Quarters Hotel Downtown, Houston
Blossom Hotel Houston
City view
Blossom Hotel Houston
4.0 star property
9.2 out of 10, Wonderful, (2279)
"Everything was extremely nice! The people, the hotel, the room. We loved it!"
The price is 4.070.582 ₫
per night
28 Jul - 29 Jul
Blossom Hotel Houston
The Whitehall Houston
City view from property
The Whitehall Houston
4.0 star property
8.2 out of 10, Very good, (1002)
"Great service from Neil and staff."
The price is 4.047.822 ₫
per night
30 Jun - 1 Jul
The Whitehall Houston
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
8.0 out of 10, Very good, (1038)
"Good location. Great stay for price. Lines for elevators, could have just been a busy weekend. Room could use an upgrade, not as clean as I’d expect. Overall decent. "
The price is 2.631.339 ₫
per night
27 Jul - 28 Jul
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Marriott Marquis Houston
2 outdoor pools, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis Houston
4.0 star property
8.8 out of 10, Excellent, (1009)
"The pool area had a strange smell and the towels needed to be upgraded. Most were torn and stained. "
The price is 5.524.386 ₫
per night
5 Jul - 6 Jul
Marriott Marquis Houston
Hilton Americas-Houston
Exterior
Hilton Americas-Houston
4.0 star property
9.2 out of 10, Wonderful, (1076)
"Excellent "
The price is 4.739.007 ₫
per night
6 Jul - 7 Jul
Hilton Americas-Houston
Cambria Hotel Houston Downtown Convention Center
Lobby
Cambria Hotel Houston Downtown Convention Center
3.0 star property
8.8 out of 10, Excellent, (1336)
"Elevator not all working"
The price is 2.791.470 ₫
per night
4 Jul - 5 Jul
Cambria Hotel Houston Downtown Convention Center
Hyatt Place Houston Downtown
Lobby sitting area
Hyatt Place Houston Downtown
3.0 star property
9.0 out of 10, Wonderful, (1316)
"Very friendly staff, room was spacious, clean and super comfortable. Would stay here again!"
The price is 3.873.435 ₫
per night
2 Jul - 3 Jul
Hyatt Place Houston Downtown
The Royal Sonesta Houston Galleria
Exterior
The Royal Sonesta Houston Galleria
4.0 star property
8.0 out of 10, Very good, (1007)
"Great Experience "
The price is 4.329.133 ₫
per night
4 Jul - 5 Jul
The Royal Sonesta Houston Galleria
Hotel Derek
Suite, 1 King Bed, City View | View from room
Hotel Derek
4.0 star property
6.4 out of 10, (2164)
"My room had a lot of nets and mosquitoes. I woke up with bite marks all over my arms and legs."
The price is 3.238.258 ₫
per night
30 Jun - 1 Jul
Hotel Derek
Hyatt Regency Houston
City view
Hyatt Regency Houston
4.0 star property
9.0 out of 10, Wonderful, (1649)
"Amazing "
The price is 3.643.040 ₫
per night
1 Jul - 2 Jul
Hyatt Regency Houston
HYATT house Houston/Galleria
Outdoor pool
HYATT house Houston/Galleria
3.0 star property
8.4 out of 10, Very good, (2123)
"An older hotel, but kept in good condition. Front desk staff was very pleasant. Convenient location to shopping."
The price is 3.440.649 ₫
per night
16 Jul - 17 Jul
HYATT house Houston/Galleria
The Post Oak Hotel at Uptown Houston
Outdoor pool, pool cabanas (surcharge), pool umbrellas
The Post Oak Hotel at Uptown Houston
5.0 star property
9.6 out of 10, Exceptional, (627)
"Very happy with the hotel and stuff. Very clean n beautiful place."
The price is 14.256.480 ₫
per night
14 Jul - 15 Jul
The Post Oak Hotel at Uptown Houston
C. Baldwin, Curio Collection by Hilton
Outdoor banquet area
C. Baldwin, Curio Collection by Hilton
4.0 star property
8.2 out of 10, Very good, (731)
"Great stay!"
The price is 3.844.413 ₫
per night
2 Jul - 3 Jul
C. Baldwin, Curio Collection by Hilton
Hyatt Place Houston Medical Center
Lobby
Hyatt Place Houston Medical Center
3.0 star property
9.2 out of 10, Wonderful, (790)
"The property was nice, modern, and clean. The only thing negative that I have to say is that the parking garage elevator broke during our stay, so me and my party had to take the stairs. Also hotel staff did not bring extra towels up to our room as requested. Otherwise it was a good stay. "
The price is 3.184.796 ₫
per night
5 Jul - 6 Jul
Hyatt Place Houston Medical Center
Hyatt Place Houston/Galleria
Lobby
Hyatt Place Houston/Galleria
3.0 star property
8.2 out of 10, Very good, (1565)
"Friendly staff"
The price is 3.786.114 ₫
per night
30 Jun - 1 Jul
Hyatt Place Houston/Galleria
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers
Hyatt Regency Houston/Galleria
4.0 star property
8.4 out of 10, Very good, (1498)
"Beautiful hotel and amenities. Comfortable bed and nice staff. Would stay again."
The price is 4.137.943 ₫
per night
1 Jul - 2 Jul
Hyatt Regency Houston/Galleria
Courtyard by Marriott Houston Medical Center/NRG Park
Outdoor pool, pool umbrellas
Courtyard by Marriott Houston Medical Center/NRG Park
3.0 star property
8.4 out of 10, Very good, (1005)
"Had a bit of a hard time checking in because person at front was a bit difficult. But property is great!"
The price is 2.497.430 ₫
per night
29 Jun - 30 Jun
Courtyard by Marriott Houston Medical Center/NRG Park
Holiday Inn Houston Downtown, an IHG Hotel
Property amenity
Holiday Inn Houston Downtown, an IHG Hotel
3.0 star property
8.4 out of 10, Very good, (1011)
"This is our go-to hotel in the Minute Maid Park/George R Brown area. We have stayed at least 10 times. Staff is super courteous and helpful. Breakfast is good and the hotel is always clean."
The price is 3.051.141 ₫
per night
5 Jul - 6 Jul
Holiday Inn Houston Downtown, an IHG Hotel
InterContinental Houston, an IHG Hotel
International cuisine
InterContinental Houston, an IHG Hotel
4.0 star property
9.4 out of 10, Exceptional, (1006)
"They got us a great room looking over Rice campus like I requested. The bed was comfortable and everything was clean."
The price is 3.411.372 ₫
per night
6 Jul - 7 Jul
InterContinental Houston, an IHG Hotel
Don't see what you're looking for?
See all available properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around South Main

Hotels in top Houston neighborhoods Learn more about South Main
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

3 out of top 10 points of interest in this area
4/5(25 area reviews)

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Downtown Aquarium – discover Downtown Houston, a destination also famous for its sports teams.

Find hotels in Downtown Houston

South Main hotels information

Number of reviews
28,160
Accommodation
6,294 hotels
Lowest Price
2.321.770 ₫
Highest Price
14.256.480 ₫

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 83 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.